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Genetic alterations of IDH1 and Vegf in brain tumors

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This study evaluates the presence of R132H mutation in isocitrate dehydrogenase (IDH1) gene and the vascular endothelial growth factor (VEGF) +936 C/T polymorphism in brain tumors. The impact of these… Click to show full abstract

This study evaluates the presence of R132H mutation in isocitrate dehydrogenase (IDH1) gene and the vascular endothelial growth factor (VEGF) +936 C/T polymorphism in brain tumors. The impact of these genetic alterations on overall survival (OS) and progression free survival (PFS) was evaluated.

Keywords: vegf brain; idh1 vegf; genetic alterations; alterations idh1; brain; brain tumors

Journal Title: Brain and Behavior
Year Published: 2017

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