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Detection and application of neurochemical profile by multiple regional 1H‐MRS in Parkinson's disease

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The accurate diagnosis and monitoring of idiopathic Parkinson disease (PD), a progressive neurodegenerative disorder, has not been fully developed. This study sought to identify a neurochemical profile in multiple regions… Click to show full abstract

The accurate diagnosis and monitoring of idiopathic Parkinson disease (PD), a progressive neurodegenerative disorder, has not been fully developed. This study sought to identify a neurochemical profile in multiple regions of the PD brain and healthy controls by proton magnetic resonance spectroscopy (1H‐MRS). We aimed to track changes of the brain neurochemical, quantify neuronal loss, and further determine the diagnostic value of 1H‐MRS.

Keywords: parkinson disease; neurochemical profile; profile multiple; mrs

Journal Title: Brain and Behavior
Year Published: 2017

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