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Candidate therapeutic agents in a newly established triple wild‐type mucosal melanoma cell line

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Mucosal melanoma has characteristically distinct genetic features and typically poor prognosis. The lack of representative mucosal melanoma models, especially cell lines, has hindered translational research on this melanoma subtype. In… Click to show full abstract

Mucosal melanoma has characteristically distinct genetic features and typically poor prognosis. The lack of representative mucosal melanoma models, especially cell lines, has hindered translational research on this melanoma subtype. In this study, we aimed to establish and provide the biological properties, genomic features and the pharmacological profiles of a mucosal melanoma cell line that would contribute to the understanding and treatment optimization of molecularly‐defined mucosal melanoma subtype.

Keywords: mucosal melanoma; melanoma cell; cell line; melanoma

Journal Title: Cancer Communications
Year Published: 2022

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