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LINC01224 accelerates malignant transformation via MiR‐193a‐5p/CDK8 axis in gastric cancer

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Gastric cancer (GC) is a malignant tumor with a significantly high mortality rate, yet, its pathogenesis is not fully understood. Bioinformatics predicted that LINC01224 is highly expressed in stomach adenocarcinoma… Click to show full abstract

Gastric cancer (GC) is a malignant tumor with a significantly high mortality rate, yet, its pathogenesis is not fully understood. Bioinformatics predicted that LINC01224 is highly expressed in stomach adenocarcinoma (STAD), and showed that LINC01224 adsorbed miR‐193a‐5p to target CDK8. Therefore, this study intended to verify the effect of the LINC01224/miR‐193a‐5p/CDK8 axis on the biological behavior of gastric cancer.

Keywords: 193a cdk8; gastric cancer; cdk8 axis; mir 193a; cancer

Journal Title: Cancer Medicine
Year Published: 2021

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