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Association of miRNA targetome variants in LAMC1 and GNB3 genes with colorectal cancer and obesity

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Colorectal cancer (CRC) is one of the most common obesity‐associated cancers. Inflammation is also considered the most important factor between obesity and CRC. This study aimed to examine miRNAs binding… Click to show full abstract

Colorectal cancer (CRC) is one of the most common obesity‐associated cancers. Inflammation is also considered the most important factor between obesity and CRC. This study aimed to examine miRNAs binding sites variants on inflammatory genes identified using bioinformatics and systematic approach on clinical samples that were collected from CRC patients and controls.

Keywords: mirna targetome; colorectal cancer; targetome variants; obesity; association mirna; cancer

Journal Title: Cancer Medicine
Year Published: 2022

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