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Changes in the cervicovaginal microbiota composition of HPV16‐infected patients after clinical treatment

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High‐risk human papillomavirus (hrHPV) infection is a key factor that alters cervicovaginal microbiota patterns and causes cervical intraepithelial neoplasias (CINs) or even cervical cancer. Although local excisional treatment can clear… Click to show full abstract

High‐risk human papillomavirus (hrHPV) infection is a key factor that alters cervicovaginal microbiota patterns and causes cervical intraepithelial neoplasias (CINs) or even cervical cancer. Although local excisional treatment can clear hrHPV infection and restore the cervicovaginal microbiota, it is unclear which cervicovaginal microbiota represents recovery. Our objective was to describe the cervicovaginal microbiota before and after treatments and to assess the association between the microbiota and HPV persistence.

Keywords: cervicovaginal microbiota; composition hpv16; microbiota; changes cervicovaginal; microbiota composition; treatment

Journal Title: Cancer Medicine
Year Published: 2022

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