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BRD9 is an essential regulator of glycolysis that creates an epigenetic vulnerability in colon adenocarcinoma

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The intensive interplay between aberrant epigenetic events and metabolic remodeling represents one of the hallmarks of tumors, including colon cancer. The functions of Bromodomain Containing Protein BRD‐9 in colon cancer… Click to show full abstract

The intensive interplay between aberrant epigenetic events and metabolic remodeling represents one of the hallmarks of tumors, including colon cancer. The functions of Bromodomain Containing Protein BRD‐9 in colon cancer remains indefinite. We aimed to identify the biological roles and clinical significance of BRD9 in colon cancer.

Keywords: essential regulator; brd9 essential; regulator glycolysis; colon cancer; cancer; colon

Journal Title: Cancer Medicine
Year Published: 2022

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