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Identification of Ferroptosis‐related molecular model and immune subtypes of hepatocellular carcinoma for individual therapy

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Excessive iron accumulation and lipid peroxidation are primary characteristics of ferroptosis in hepatocellular carcinoma (HCC). Ferroptosis inducer combined with immunotherapy has become a new hope for HCC patients. Therefore, the… Click to show full abstract

Excessive iron accumulation and lipid peroxidation are primary characteristics of ferroptosis in hepatocellular carcinoma (HCC). Ferroptosis inducer combined with immunotherapy has become a new hope for HCC patients. Therefore, the construction and validation of subtype‐specific sensitivity to ferroptosis inducer will be helpful for hierarchical management and precise individual therapy.

Keywords: hepatocellular carcinoma; individual therapy; ferroptosis related; identification ferroptosis; ferroptosis

Journal Title: Cancer Medicine
Year Published: 2022

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