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The structural maintenance of chromosomes 5 is a possible biomarker for individualized treatment of colorectal cancer

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Although the understanding of resistance to oxaliplatin (OXA) chemotherapy in colorectal cancer (CRC) has been sought for many years, drug tolerance remains a major challenge for cancer therapy. Revealing the… Click to show full abstract

Although the understanding of resistance to oxaliplatin (OXA) chemotherapy in colorectal cancer (CRC) has been sought for many years, drug tolerance remains a major challenge for cancer therapy. Revealing the molecular mechanism of OXA resistance could help to explain the poor prognosis of patients.

Keywords: cancer; structural maintenance; possible biomarker; colorectal cancer; maintenance chromosomes; chromosomes possible

Journal Title: Cancer Medicine
Year Published: 2022

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