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XPO1 mediates the nuclear export of several proteins, mainly tumor suppressors. KPT‐330 (Selinexor) is a selective inhibitor of XPO1 that has demonstrated good therapeutic effects in hematologic cancers. Click to show full abstract
XPO1 mediates the nuclear export of several proteins, mainly tumor suppressors. KPT‐330 (Selinexor) is a selective inhibitor of XPO1 that has demonstrated good therapeutic effects in hematologic cancers.
Keywords:
cell proliferation;
xpo1;
cholangiocarcinoma cell;
inhibition xpo1;
xpo1 impairs;
impairs cholangiocarcinoma
Journal Title: Cancer Medicine
Year Published: 2022
Link to full text (if available)
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Journal Title: Cancer Medicine
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!