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Tumor immune microenvironment in therapy‐naive esophageal adenocarcinoma could predict the nodal status

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Currently, preoperative staging of esophageal adenocarcinoma (EAC) has modest reliability and accuracy for pT and pN stages prediction, which heavily affects overall survival. The interplay among immune checkpoints, oncogenes, and… Click to show full abstract

Currently, preoperative staging of esophageal adenocarcinoma (EAC) has modest reliability and accuracy for pT and pN stages prediction, which heavily affects overall survival. The interplay among immune checkpoints, oncogenes, and intratumoral and peritumoral immune infiltrating cells could be used to predict loco‐regional metastatic disease in early EAC.

Keywords: therapy naive; immune microenvironment; tumor immune; microenvironment therapy; adenocarcinoma; esophageal adenocarcinoma

Journal Title: Cancer Medicine
Year Published: 2022

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