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Chemotherapy for locoregionally advanced nasopharyngeal carcinoma: Who really needs it

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The CSCO and ASCO guidelines in 2021 recommend chemotherapy for stage III–IVA (8th edition of AJCC staging) nasopharyngeal carcinoma (NPC). Actually, patients with stage T3–4N0M0 are often excluded from various… Click to show full abstract

The CSCO and ASCO guidelines in 2021 recommend chemotherapy for stage III–IVA (8th edition of AJCC staging) nasopharyngeal carcinoma (NPC). Actually, patients with stage T3–4N0M0 are often excluded from various clinical trials of the locoregionally advanced NPC, and the survival benefit of chemotherapy in such patients has always been controversial. This study aims to explore the benefit of chemotherapy in patients with locoregionally advanced NPC, especially those with negative lymph nodes.

Keywords: nasopharyngeal carcinoma; advanced nasopharyngeal; locoregionally advanced; chemotherapy locoregionally; chemotherapy

Journal Title: Cancer Medicine
Year Published: 2022

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