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Intratumoral heterogeneity, treatment response, and survival outcome of ER‐positive HER2‐positive breast cancer

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ER+HER2+ breast cancer requires most types of systemic therapies perioperatively. However, treatment resistance is often experienced. The current study investigated the predictive and prognostic value of intratumoral heterogeneity and conventional… Click to show full abstract

ER+HER2+ breast cancer requires most types of systemic therapies perioperatively. However, treatment resistance is often experienced. The current study investigated the predictive and prognostic value of intratumoral heterogeneity and conventional clinicopathological factors in patients with ER+HER2+ breast cancer.

Keywords: her2; breast cancer; treatment; cancer; intratumoral heterogeneity

Journal Title: Cancer Medicine
Year Published: 2023

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