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Reducing Home Labs for Pediatric Patients With Solid Tumors: Impact of a Novel Clinical Practice Guideline on Safety, Cost, and Quality of Life

For pediatric patients with solid tumors, the use of growth factors following chemotherapy evolved from daily filgrastim to pegylated filgrastim. Currently, post‐chemotherapy laboratory work is obtained to monitor for transfusion… Click to show full abstract

For pediatric patients with solid tumors, the use of growth factors following chemotherapy evolved from daily filgrastim to pegylated filgrastim. Currently, post‐chemotherapy laboratory work is obtained to monitor for transfusion needs rather than count recovery. We implemented a clinical practice improvement project aimed at identifying the minimum number of labs required to assess transfusion needs, based upon disease and chemotherapeutic regimen, to design guidelines to safely reduce the number of home labs for targeted solid tumor diagnoses by 50% over 2 years.

Keywords: home labs; solid tumors; pediatric patients; patients solid; clinical practice

Journal Title: Cancer Medicine
Year Published: 2025

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