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We report a fluorescent probe that is highly sensitive and selective for serum albumins. Signal transduction results from the disassembly of fluorescence‐quenched aggregates upon binding to human serum albumin (HSA).… Click to show full abstract
We report a fluorescent probe that is highly sensitive and selective for serum albumins. Signal transduction results from the disassembly of fluorescence‐quenched aggregates upon binding to human serum albumin (HSA). The probe offers a rapid (≤2 s) fluorometric assay of HSA in phosphate‐buffered saline, urine, or blood serum with a high signal‐to‐noise ratio. It is also useful as a wash‐free prestaining reagent for detecting HSA on electrophoresis gels.
Keywords:
fluorophore aggregates;
electrophoresis;
selective detection;
electrophoresis gels;
colloidal fluorophore;
aggregates selective
Journal Title: ChemBioChem
Year Published: 2019
Link to full text (if available)
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Journal Title: ChemBioChem
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!