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Among the non‐canonical structures of B‐DNA, the G‐quadruplex is of particular interest because of its well‐defined conformation, high stability, and versatility. Herein we report our studies on the development of… Click to show full abstract
Among the non‐canonical structures of B‐DNA, the G‐quadruplex is of particular interest because of its well‐defined conformation, high stability, and versatility. Herein we report our studies on the development of an amide‐linked minimal diguanosinyl motif that forms a G‐quadruplex‐like structure in solution in the presence of potassium cations; various linear guanosine amino acid dimers were synthesized with linkers of different chain lengths to investigate the optimum flexibility required to form such structures.
Journal Title: ChemBioChem
Year Published: 2020
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