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Polypyridyl Ruthenium(II) Complexes with Red‐Shifted Absorption: New Promises in Photodynamic Therapy

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In the field of cancer photodynamic therapy (PDT) research, development of metal‐based PDT drugs that can be used under red light exposure is the “holy grail” to achieve. This highlight… Click to show full abstract

In the field of cancer photodynamic therapy (PDT) research, development of metal‐based PDT drugs that can be used under red light exposure is the “holy grail” to achieve. This highlight highlighted few current literatures on polypyridyl‐based Ru(II) complexes with significantly red‐shifted absorption to achieve in‐vitro and in‐vivo PDT effect in 540–600 nm light. The enormous potential of judicial ligand choice and in‐silico optimization to achieve the red light, metal‐based PDT drugs are discussed.

Keywords: pdt; photodynamic therapy; shifted absorption; red shifted

Journal Title: ChemBioChem
Year Published: 2021

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