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Three versus 12‐month dual antiplatelet therapy duration in patients with acute coronary syndrome undergoing percutaneous coronary intervention: A meta‐analysis of randomized controlled trials

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The American Heart Association/American College of Cardiology guidelines on dual antiplatelet therapy (DAPT) recommend at least 12 months of a P2Y12 inhibitor and low dose aspirin in patients with an… Click to show full abstract

The American Heart Association/American College of Cardiology guidelines on dual antiplatelet therapy (DAPT) recommend at least 12 months of a P2Y12 inhibitor and low dose aspirin in patients with an acute coronary syndrome (ACS) treated with a stent. Since that recommendation, several randomized controlled trials (RCTs) have studied an abbreviated duration of DAPT in ACS. Therefore, we sought to perform a meta‐analysis of RCTs comparing 3‐ versus 12‐month DAPT in patients presenting with ACS undergoing percutaneous coronary intervention (PCI).

Keywords: coronary syndrome; randomized controlled; acute coronary; antiplatelet therapy; dual antiplatelet; patients acute

Journal Title: Catheterization and Cardiovascular Interventions
Year Published: 2022

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