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KIO3‐Catalyzed Domino C(sp2)−H Bond Sulfenylation and C−N Bond Oxygenation of Enaminones toward the Synthesis of 3‐Sulfenylated Chromones

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With 2‐hydroxyphenyl‐functionalized enaminones and thiophenols as the starting materials, the facile synthesis of 3‐sulfenylated chromones has been realized through a KIO3‐catalyzed domino reaction of C−H sulfenylation and subsequent C−N‐cleavage‐based C−O… Click to show full abstract

With 2‐hydroxyphenyl‐functionalized enaminones and thiophenols as the starting materials, the facile synthesis of 3‐sulfenylated chromones has been realized through a KIO3‐catalyzed domino reaction of C−H sulfenylation and subsequent C−N‐cleavage‐based C−O bond formation. The reaction was performed under transition‐metal‐free conditions in ethyl lactate, a bioavailable ecofriendly medium.

Keywords: bond; synthesis sulfenylated; kio3 catalyzed; catalyzed domino; sulfenylated chromones

Journal Title: ChemCatChem
Year Published: 2017

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