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Highly Stereoselective Synthesis of Imidazolidines through the Palladium(0)‐Catalyzed Three‐Component Reaction of 2,3‐Allenylamines, Organic Halides, and Imines

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A new and efficient method for the synthesis of polysubstituted imidazolidines through the Pd0‐catalyzed double addition/cyclization of 2,3‐allenylamines with aryl iodides and imines was explored. This catalytic reaction afforded the… Click to show full abstract

A new and efficient method for the synthesis of polysubstituted imidazolidines through the Pd0‐catalyzed double addition/cyclization of 2,3‐allenylamines with aryl iodides and imines was explored. This catalytic reaction afforded the desired products in good yields with high diastereoselectivities.

Keywords: highly stereoselective; imidazolidines palladium; stereoselective synthesis; synthesis imidazolidines; reaction; synthesis

Journal Title: ChemCatChem
Year Published: 2017

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