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The asymmetric isomerization of primary allylic alcohols to chiral aldehydes using iridium‐catalysts bearing P,N‐MaxPHOX ligands has been studied. These catalysts can be fine‐tuned as they present three different stereogenic centers… Click to show full abstract
The asymmetric isomerization of primary allylic alcohols to chiral aldehydes using iridium‐catalysts bearing P,N‐MaxPHOX ligands has been studied. These catalysts can be fine‐tuned as they present three different stereogenic centers to modulate both the reactivity and enantioselectivity of a family of different substrates. The experimental part is supported by a DFT study of the reaction mechanism, which provides new insights into the key steps of this transformation.
Keywords:
primary allylic;
asymmetric isomerization;
maxphox ligands;
allylic alcohols;
isomerization primary
Journal Title: ChemCatChem
Year Published: 2020
Link to full text (if available)
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Journal Title: ChemCatChem
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!