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Altered profile of circulating microparticles in nonvalvular atrial fibrillation

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Nonvalvular atrial fibrillation (AF) is the most common cardiac arrhythmia, and it is associated with the prothrombotic state. Circulating microparticles (cMPs) are membrane vesicles that are shed from many cell… Click to show full abstract

Nonvalvular atrial fibrillation (AF) is the most common cardiac arrhythmia, and it is associated with the prothrombotic state. Circulating microparticles (cMPs) are membrane vesicles that are shed from many cell types in response to cell activation and cell apoptosis. Several studies reported that cMPs may play a role in the hypercoagulable state that can be observed in patients with AF. The aim of this study was to determine the levels of total cMPs and characterize their cellular origins in AF patients.

Keywords: atrial fibrillation; nonvalvular atrial; altered profile; circulating microparticles; profile circulating

Journal Title: Clinical Cardiology
Year Published: 2019

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