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Fumio Oosawa and his colleagues at Nagoya University laid the foundation for mechanistic studies of actin. Using relatively primitive tools they discovered that actin monomers assemble in a two‐step mechanism:… Click to show full abstract
Fumio Oosawa and his colleagues at Nagoya University laid the foundation for mechanistic studies of actin. Using relatively primitive tools they discovered that actin monomers assemble in a two‐step mechanism: highly unfavorable formation of small oligomeric nuclei followed by rapid elongation. Oosawa and his student Sadashi Hatano were the first to purify actin from a nonmuscle cell, Physarum polycephalum, initiating studies of the molecular mechanism of cellular movements.
Keywords:
pioneer actin;
actin biophysics;
fumio oosawa;
oosawa pioneer;
biophysics;
tribute fumio
Journal Title: Cytoskeleton
Year Published: 2017
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Journal Title: Cytoskeleton
Year Published: 2017
Link to full text (if available)
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recommendations!