Photo by bermixstudio from unsplash
Selective leads: In this study, we generated a new series of serotonin 5-HT7 receptor antagonists. Their synthesis, structure-activity relationships, and selectivity profiles are reported. This series includes 5-HT7 antagonists with… Click to show full abstract
Selective leads: In this study, we generated a new series of serotonin 5-HT7 receptor antagonists. Their synthesis, structure-activity relationships, and selectivity profiles are reported. This series includes 5-HT7 antagonists with unprecedented high selectivity for the 5-HT7 receptor, setting the stage for lead optimization of drugs acting on a range of neurological targets.
Keywords:
antagonists unprecedented;
ht7 receptor;
unprecedented selectivity;
receptor antagonists;
receptor
Journal Title: ChemMedChem
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: ChemMedChem
Year Published: 2018
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!