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Mesothelium expression of vascular cell adhesion molecule‐1 (VCAM‐1) is associated with an unfavorable prognosis in epithelial ovarian cancer (EOC)

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Mesothelium vascular cell adhesion molecule‐1 (VCAM‐1) expression in the metastatic epithelial ovarian cancer (EOC) microenvironment is induced by tumor and mediates tumor cell invasion. VCAM‐1 imaging suggests expression during treatment… Click to show full abstract

Mesothelium vascular cell adhesion molecule‐1 (VCAM‐1) expression in the metastatic epithelial ovarian cancer (EOC) microenvironment is induced by tumor and mediates tumor cell invasion. VCAM‐1 imaging suggests expression during treatment is an indicator of platinum resistance. Here, we assess the potential prognostic significance of mesothelium VCAM‐1 expression and prospectively evaluate whether soluble VCAM‐1 (sVCAM‐1) is a surrogate for mesothelium expression.

Keywords: vascular cell; expression; cancer; mesothelium; vcam

Journal Title: Cancer
Year Published: 2017

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