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Young adult survivors of childhood acute lymphoblastic leukemia show evidence of chronic inflammation and cellular aging

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Large epidemiologic studies have reported the premature onset of age‐related conditions, such as ischemic heart disease and diabetes mellitus, in childhood cancer survivors, decades earlier than in their peers. The… Click to show full abstract

Large epidemiologic studies have reported the premature onset of age‐related conditions, such as ischemic heart disease and diabetes mellitus, in childhood cancer survivors, decades earlier than in their peers. The authors investigated whether young adult survivors of childhood acute lymphoblastic leukemia (ALL) have a biologic phenotype of cellular ageing and chronic inflammation.

Keywords: childhood acute; young adult; adult survivors; lymphoblastic leukemia; acute lymphoblastic; survivors childhood

Journal Title: Cancer
Year Published: 2017

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