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Second tyrosine kinase inhibitor discontinuation attempt in patients with chronic myeloid leukemia

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Several studies have demonstrated that approximately one‐half of patients with chronic myeloid leukemia (CML) who receive treatment with tyrosine kinase inhibitors (TKIs) and achieve and maintain a deep molecular response… Click to show full abstract

Several studies have demonstrated that approximately one‐half of patients with chronic myeloid leukemia (CML) who receive treatment with tyrosine kinase inhibitors (TKIs) and achieve and maintain a deep molecular response (DMR) are able to successfully discontinue therapy. In patients who have a molecular relapse, a DMR is rapidly regained upon treatment re‐initiation.

Keywords: myeloid leukemia; tyrosine kinase; patients chronic; chronic myeloid

Journal Title: Cancer
Year Published: 2017

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