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Cytogenetic clonal evolution in myelodysplastic syndromes is associated with inferior prognosis

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The karyotype of bone marrow cells at the time of diagnosis is a strong prognostic parameter for overall survival as well as acute myeloid leukemia (AML) progression in patients with… Click to show full abstract

The karyotype of bone marrow cells at the time of diagnosis is a strong prognostic parameter for overall survival as well as acute myeloid leukemia (AML) progression in patients with myelodysplastic syndromes (MDS). However, to the authors' knowledge, few data exist regarding the prognostic impact of cytogenetic clonal evolution during the course of MDS.

Keywords: clonal evolution; myelodysplastic syndromes; cytogenetic clonal; syndromes associated; evolution myelodysplastic

Journal Title: Cancer
Year Published: 2017

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