The improving efficacy of cancer treatment has resulted in an increasing array of treatment‐related symptoms and associated burdens imposed on individuals undergoing aggressive treatment of their disease. Often, clinical trials… Click to show full abstract
The improving efficacy of cancer treatment has resulted in an increasing array of treatment‐related symptoms and associated burdens imposed on individuals undergoing aggressive treatment of their disease. Often, clinical trials compare therapies that have different types, and severities, of adverse effects. Whether rated by clinicians or patients themselves, it can be difficult to know which side effect profile is more disruptive or bothersome to patients. A simple summary index of bother can help to adjudicate the variability in adverse effects across treatments being compared with each other.
               
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