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Neuroblastoma is the most frequently diagnosed extracranial solid tumor in children. Previous studies have shown that single‐nucleotide polymorphisms in some genes are associated with the risk of multiple cancers, including… Click to show full abstract
Neuroblastoma is the most frequently diagnosed extracranial solid tumor in children. Previous studies have shown that single‐nucleotide polymorphisms in some genes are associated with the risk of multiple cancers, including neuroblastoma. Although Hox transcript antisense intergenic RNA (HOTAIR) gene polymorphisms have been investigated in a variety of cancers, to the authors' knowledge the relationships between HOTAIR gene polymorphisms and neuroblastoma susceptibility have not been reported to date. The objective of the current study was to evaluate the correlation between HOTAIR gene polymorphisms and neuroblastoma risk in Chinese children.
Journal Title: Cancer
Year Published: 2018
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