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Results of second salvage therapy in 673 adults with acute myelogenous leukemia treated at a single institution since 2000

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The prognosis is poor for patients who have relapsed‐refractory acute myelogenous leukemia (AML). Most published reports analyzed results from therapies in first‐salvage AML or in studies that were conducted before… Click to show full abstract

The prognosis is poor for patients who have relapsed‐refractory acute myelogenous leukemia (AML). Most published reports analyzed results from therapies in first‐salvage AML or in studies that were conducted before 2000. Several novel agents and strategies are being tested for potential approval as treatment for patients with relapsed‐refractory AML in second salvage. Therefore, it is important to establish the historic results of anti‐AML therapies in this setting in the modern era. The objective of the current study was to analyze the results from second salvage therapies in patients with AML since 2000 with regard to response and survival.

Keywords: since 2000; results second; myelogenous leukemia; second salvage; acute myelogenous

Journal Title: Cancer
Year Published: 2018

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