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Analyzing the clinical actionability of germline pharmacogenomic findings in oncology

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Germline and tumor pharmacogenomics impact drug responses, but germline markers less commonly guide oncology prescribing. The authors hypothesized that a critical number of clinically actionable germline pharmacogenomic associations exist, representing… Click to show full abstract

Germline and tumor pharmacogenomics impact drug responses, but germline markers less commonly guide oncology prescribing. The authors hypothesized that a critical number of clinically actionable germline pharmacogenomic associations exist, representing clinical implementation opportunities.

Keywords: analyzing clinical; germline pharmacogenomic; actionability germline; pharmacogenomic findings; clinical actionability; oncology

Journal Title: Cancer
Year Published: 2018

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