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Addition of eltrombopag to immunosuppressive therapy in patients with newly diagnosed aplastic anemia

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The immune‐mediated destruction of hematopoietic stem cells is implicated in the pathophysiology of aplastic anemia (AA). Immunosuppressive therapy (IST) using antithymocyte globulin and cyclosporine is successful in this setting. Eltrombopag… Click to show full abstract

The immune‐mediated destruction of hematopoietic stem cells is implicated in the pathophysiology of aplastic anemia (AA). Immunosuppressive therapy (IST) using antithymocyte globulin and cyclosporine is successful in this setting. Eltrombopag is active in patients with refractory AA, presumably by increasing the bone marrow progenitors.

Keywords: eltrombopag immunosuppressive; immunosuppressive therapy; addition eltrombopag; aplastic anemia

Journal Title: Cancer
Year Published: 2018

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