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Cognitive performance in survivors of breast cancer and markers of biological aging

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Biological aging pathways accelerated by cancer treatments may be a mechanism for cognitive impairment in cancer survivors. The goal of the current study was to examine whether indicators of biological… Click to show full abstract

Biological aging pathways accelerated by cancer treatments may be a mechanism for cognitive impairment in cancer survivors. The goal of the current study was to examine whether indicators of biological aging, namely elevated levels of DNA damage, reduced telomerase enzymatic activity, and shorter peripheral blood mononuclear cell (PBMC) telomere length (TL) would be related to cognitive function in a cohort of survivors of breast cancer.

Keywords: performance survivors; cognitive performance; breast cancer; survivors breast; cancer; biological aging

Journal Title: Cancer
Year Published: 2019

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