After treatment of primary breast cancer, endocrine therapy (ET) is prescribed for patients with hormone receptor–positive cancers. Despite ET recommendations of 5 to 10 years of treatment, to the authors’… Click to show full abstract
After treatment of primary breast cancer, endocrine therapy (ET) is prescribed for patients with hormone receptor–positive cancers. Despite ET recommendations of 5 to 10 years of treatment, to the authors’ knowledge there is little prospective study of its impact on cognitive function over an extended period of time. ET has known pharmacologic effects on the brain. Cognitive side effects are a concern for many women, with mixed findings reported in various studies. The current prospective longitudinal study examined the neuropsychological effects of ET over time, up to 6 years after treatment.
               
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