Modern disease staging systems have restructured human papillomavirus (HPV)‐negative (HPV−) and HPV‐positive (HPV+) oropharyngeal carcinoma (OPC) into distinct pathologic nodal systems. Given that quantitative lymph node (LN) burden is the… Click to show full abstract
Modern disease staging systems have restructured human papillomavirus (HPV)‐negative (HPV−) and HPV‐positive (HPV+) oropharyngeal carcinoma (OPC) into distinct pathologic nodal systems. Given that quantitative lymph node (LN) burden is the dominant prognostic factor in most head and neck cancers, we investigated whether HPV− and HPV+ OPC warrant divergent pathologic nodal classification.
               
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