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Impact of obesity and white adipose tissue inflammation on the omental microenvironment in endometrial cancer

A complex relationship between adipose tissue and malignancy, involving an inflammatory response, has been reported. The goal of this work was to assess the prevalence of white adipose tissue (WAT)… Click to show full abstract

A complex relationship between adipose tissue and malignancy, involving an inflammatory response, has been reported. The goal of this work was to assess the prevalence of white adipose tissue (WAT) inflammation in patients with endometrial cancer (EC), and the association with circulating inflammation markers. Furthermore, the aim was to characterize the pathways activated in and the cell type composition of adipose tissue in patients with EC.

Keywords: endometrial cancer; inflammation; adipose tissue; white adipose; tissue

Journal Title: Cancer
Year Published: 2022

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