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Venous and arterial thrombosis associated with abemaciclib therapy for metastatic breast cancer

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The CDK4/6 inhibitor abemaciclib is a mainstay of treatment for hormone receptor–positive breast cancer. However, increased venous thromboembolism (VTE) rates in multiple clinical trials resulted in a black‐box warning for… Click to show full abstract

The CDK4/6 inhibitor abemaciclib is a mainstay of treatment for hormone receptor–positive breast cancer. However, increased venous thromboembolism (VTE) rates in multiple clinical trials resulted in a black‐box warning for this agent. Thrombosis rates in unselected real‐world populations receiving abemaciclib remain ill defined.

Keywords: cancer venous; breast cancer; venous arterial; thrombosis; cancer

Journal Title: Cancer
Year Published: 2022

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