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Landscape and clinical impact of NOTCH mutations in newly diagnosed acute myeloid leukemia

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NOTCH mutations (NOTCHmut) are recognized as major oncogenic drivers associated with controversial clinical impact on T‐cell acute lymphoblastic leukemia (T‐ALL), whereas their clinical value on acute myeloid leukemia (AML) is… Click to show full abstract

NOTCH mutations (NOTCHmut) are recognized as major oncogenic drivers associated with controversial clinical impact on T‐cell acute lymphoblastic leukemia (T‐ALL), whereas their clinical value on acute myeloid leukemia (AML) is poorly defined.

Keywords: myeloid leukemia; notch mutations; leukemia; acute myeloid; clinical impact

Journal Title: Cancer
Year Published: 2022

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