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Performance of repeat cytology with reflex ThyroSeq genomic classifier for indeterminant thyroid cytology

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The American Thyroid Association recommends either repeat fine‐needle aspiration biopsy (FNAB) or molecular testing (eg, ThyroSeq) of Bethesda category III (atypia of undetermined significance/follicular lesion of undetermined significance [AUS/FLUS]) nodules… Click to show full abstract

The American Thyroid Association recommends either repeat fine‐needle aspiration biopsy (FNAB) or molecular testing (eg, ThyroSeq) of Bethesda category III (atypia of undetermined significance/follicular lesion of undetermined significance [AUS/FLUS]) nodules to provide further risk stratification. How a testing algorithm that uses ancillary molecular tests performs as a reflex test for repeat sampling of indeterminant nodules remains unclear.

Keywords: thyroseq; repeat cytology; cytology reflex; repeat; performance repeat; cytology

Journal Title: Cancer Cytopathology
Year Published: 2022

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