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Significance of KRAS mutation testing in biliary brushing cytology specimens: A 10‐year retrospective review

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Biliary strictures can be caused by benign and malignant conditions. A biliary duct brushing diagnosis can be challenging because of low cellularity and overlapping morphology among different entities, leading to… Click to show full abstract

Biliary strictures can be caused by benign and malignant conditions. A biliary duct brushing diagnosis can be challenging because of low cellularity and overlapping morphology among different entities, leading to a variable reported sensitivity. This study aimed to assess the value of KRAS mutation testing in adding cytological diagnosis of biliary duct brushings.

Keywords: significance kras; mutation testing; testing biliary; cytology; kras mutation

Journal Title: Cancer Cytopathology
Year Published: 2022

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