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Cytohistologic immunohistochemical correlation of epithelial tubo‐ovarian neoplasms: Can cell blocks substitute for tissue?

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Cytologic specimens often represent the initial diagnostic material for tubo‐ovarian neoplasms resulting from therapeutic paracentesis for patients presenting with high‐volume ascites. However, subtyping and immunohistochemical (IHC) characterization, which have implications… Click to show full abstract

Cytologic specimens often represent the initial diagnostic material for tubo‐ovarian neoplasms resulting from therapeutic paracentesis for patients presenting with high‐volume ascites. However, subtyping and immunohistochemical (IHC) characterization, which have implications in preoperative management and downstream ancillary testing, are not routinely performed in many institutions. This study aims to perform cytohistologic correlation of commonly used IHC stains to establish their reliability in peritoneal fluids/washing specimens.

Keywords: ovarian neoplasms; cytohistologic immunohistochemical; tubo ovarian; immunohistochemical correlation

Journal Title: Cancer Cytopathology
Year Published: 2022

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