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Neural architecture influences rTMS-induced functional change: a DTI and FMRI study of cue-reactivity modulation in alcohol users.

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Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neuromodulation tool which can alter neural activity in the cortical region directly under the coil as well as in monosynaptic afferent projections.… Click to show full abstract

Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neuromodulation tool which can alter neural activity in the cortical region directly under the coil as well as in monosynaptic afferent projections. Single pulses of TMS applied to the medial prefrontal cortex (MPFC), for example, can increase activity in the caudate and putamen as measured by functional MRI (1). Given that the prefrontal-striatal circuits are important for motivated behavior they have become a target for potential therapeutic rTMS interventions in addiction. This article is protected by copyright. All rights reserved.

Keywords: functional change; architecture influences; influences rtms; neural architecture; rtms induced; induced functional

Journal Title: Clinical pharmacology and therapeutics
Year Published: 2019

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