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CD163+ macrophages infiltration correlates with the immunosuppressive cytokine interleukin 10 expression in tongue leukoplakia

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Accumulating evidence suggests that macrophages are involved in the immunoediting of oral squamous cell carcinoma but the role of macrophages in oral carcinogenesis is unclear. We aimed to clarify the… Click to show full abstract

Accumulating evidence suggests that macrophages are involved in the immunoediting of oral squamous cell carcinoma but the role of macrophages in oral carcinogenesis is unclear. We aimed to clarify the role of macrophages in oral leukoplakia, which is the most common oral potentially malignant disorder from immunotolerance viewpoint.

Keywords: correlates immunosuppressive; infiltration correlates; macrophages infiltration; immunosuppressive cytokine; cytokine interleukin; cd163 macrophages

Journal Title: Clinical and Experimental Dental Research
Year Published: 2019

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