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AAV gene therapy vectors in the TMJ

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The goal of this project was to evaluate the use of two adeno‐associated viral vector serotypes, adeno‐associated viral vectors (AAV)‐2 and AAV‐6, approved for and used for gene therapy in… Click to show full abstract

The goal of this project was to evaluate the use of two adeno‐associated viral vector serotypes, adeno‐associated viral vectors (AAV)‐2 and AAV‐6, approved for and used for gene therapy in humans, for the delivery of therapeutic genes to the temporomandibular joint (TMJ) and the attendant sensory nerves.

Keywords: aav gene; therapy vectors; gene therapy; vectors tmj; gene

Journal Title: Clinical and Experimental Dental Research
Year Published: 2022

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