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Visible-Light-Driven Selective Air-oxygenation of C-H Bond via CeCl3 Catalysis in Water.

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Visible-light-induced C-H aerobic oxidation is a kind of important chemical transformations, which can be applied for the synthesis of aromatic ketones. High-cost catalysts and toxic solvents were generally needed in… Click to show full abstract

Visible-light-induced C-H aerobic oxidation is a kind of important chemical transformations, which can be applied for the synthesis of aromatic ketones. High-cost catalysts and toxic solvents were generally needed in the present methodologies. Here, an efficient aqueous C-H aerobic oxidation protocol was reported. Through CeCl 3 -mediated photocatalysis, a series of aromatic ketones were produced in moderate to excellent yields. With air as the oxidant, this reaction could be performed under mild conditions in water and demonstrates high activity and functional group tolerance. This method is economical, highly efficient and environment friendly and provide   inspiration for the development of aqueous photochemical synthesis reactions.

Keywords: water; visible light; air; selective air; driven selective; light driven

Journal Title: ChemSusChem
Year Published: 2021

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