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Immunohistochemistry Ki‐67 stain is widely used for visualizing cell proliferation. The common method for scoring the proliferation is to manually select and score a hot spot. This method is time‐consuming… Click to show full abstract
Immunohistochemistry Ki‐67 stain is widely used for visualizing cell proliferation. The common method for scoring the proliferation is to manually select and score a hot spot. This method is time‐consuming and will often not give reproducible results due to subjective selection of the hotspots and subjective scoring. An automatic hotspot detection and proliferative index scoring would be time‐saving, make the determination of the Ki‐67 score easier and minimize the uncertainty of the score by introducing a more objective and standardized score.
Journal Title: Cytometry Part A
Year Published: 2017
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