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Fine needle aspiration in intraocular metastasis from pleuropulmonary blastoma. A case report and a review of the literature

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Pleuropulmonary blastoma (PPB) is a rare primitive intrathoracic malignant neoplasm that occurs almost exclusively in children and adolescents. PPB is classified into three types according to the presence of cystic… Click to show full abstract

Pleuropulmonary blastoma (PPB) is a rare primitive intrathoracic malignant neoplasm that occurs almost exclusively in children and adolescents. PPB is classified into three types according to the presence of cystic and solid areas. We report a case of PPB with an intraocular metastasis diagnosed by fine needle aspiration (FNA): 3‐year‐old female was treated for type II PPB by neoadjuvant chemotherapy and surgery. Four years later, she presented with an intraocular lesion. To differentiate between metastasis or other malignancy, a transcleral FNA was performed and showed two cellular populations represented by roundish malignant cells and spindle‐shaped cells. The patient was treated with chemotherapy and diode laser ablation. A year later, the patient had enucleation and rare residual cells were found on the histological specimen. Patient remains disease‐free 66 months after the last surgical treatment. Diagn. Cytopathol. 2017;45:156–160. © 2016 Wiley Periodicals, Inc.

Keywords: pleuropulmonary blastoma; needle aspiration; metastasis; fine needle; intraocular metastasis

Journal Title: Diagnostic Cytopathology
Year Published: 2017

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