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A bronchial mucous gland adenoma harboring GNAS R201C mutation

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We present a case of bronchial mucous gland adenoma (MGA) and discuss the results of its cytomorphological and cytogenetic examination serving as a basis for the differential diagnosis. To our… Click to show full abstract

We present a case of bronchial mucous gland adenoma (MGA) and discuss the results of its cytomorphological and cytogenetic examination serving as a basis for the differential diagnosis. To our best knowledge, this is a first report that demonstrate a GNAS gene (R201C) mutation in mucous gland adenoma, which may play an important role in MGA tumorigenesis, as is the case in other mucinous‐type epithelial neoplasms of various organs.

Keywords: r201c mutation; bronchial mucous; gland adenoma; mucous gland

Journal Title: Diagnostic Cytopathology
Year Published: 2020

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