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Afirma gene expression classifier (GEC) is an adjunct to thyroid fine needle aspiration shown to improve pre‐operative risk assessment and reduce unnecessary surgery of indeterminate thyroid nodules. Genomic sequencing classifier… Click to show full abstract
Afirma gene expression classifier (GEC) is an adjunct to thyroid fine needle aspiration shown to improve pre‐operative risk assessment and reduce unnecessary surgery of indeterminate thyroid nodules. Genomic sequencing classifier (GSC) is a newer version aiming to improve specificity and positive predictive value (PPV) of Afirma testing. There are limited studies comparing GSC vs GEC. This study was undertaken to compare these classifiers in terms of diagnostic performance and effect on clinical management of indeterminate thyroid nodules.
Journal Title: Diagnostic Cytopathology
Year Published: 2021
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